منابع مشابه
Transmembrane helices of membrane proteins may flex to satisfy hydrophobic mismatch.
A novel mechanism for membrane modulation of transmembrane protein structure, and consequently function, is suggested in which mismatch between the hydrophobic surface of the protein and the hydrophobic interior of the lipid bilayer induces a flexing or bending of a transmembrane segment of the protein. Studies on model hydrophobic transmembrane peptides predict that helices tilt to submerge th...
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ژورنال
عنوان ژورنال: Nature
سال: 2005
ISSN: 0028-0836,1476-4687
DOI: 10.1038/438036a